How Does Mangosteen Help with Arthritis? Index Understanding The Benfits Of Mangosteen And Arthritis Drugs What Are The Side Effects From Standard NSAIDs What Is A COX-2 Inhibitor And What Are The Risks Of It? Mangosteen As Treatment For Arthritis Arthritis is a disorder characterized by painful and swollen joints. There are over 100 different forms of arthtritis and each is differentiated from the rest by observation of clinical signs and symptoms. The three most common are osteoarthritis, rheumatoid arthritis and gouty arthritis. Osteoarthritis is the most common form of arthritis and is considered as a degenerative joint disease. It is the result of trauma or infection of the joint, whereas rheumatoid arthritis is a chronic, systemic inflammatory disorder that primarily attacks the joints resulting into synovitis that often leads to the destruction of the articular cartilage. Gouty Arthritis, on the other hand, is characterized by the accumulation of uric acid crystals in the joint, causing inflammation. In case you’ve been diagnosed with arthritis, you must sit down with your doctor to discuss the best treatment regimen for you. There are plenty of drugs available to treat the disorder but there are drugs that work best for a specific type of arthritis. Patient response to these drugs also vary so it can take time to determine the kind of treatment that would work best for you. The most commonly prescribed medication for arthritis is a group of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). They are also among the most common pain relief medications used today. NSAIDs are highly effective in relieving arthritic pain but they can also have certain side effects. In order for you to better understand the mechanism of action of these drugs, you must have an idea about pain itself. Pain is basically your body’s alarm which tells you that something is wrong. Simply put, pain is the result of impulses sent from pain receptors called free nerve endings to your brain. For instance, if you have a wound, the damaged cells release compounds called prostaglandins. These chemicals are known to cause not only tissue swelling and pain but they also amplify the nerve impulses coming from the pain receptors. In short, you feel more intense pain. Pain has two major types: neuropathic and nociceptive. Neuropathic pain is normally the result of injuries to the nervous system, such as the pain associated with shingles or diabetes. On the other hand, nociceptive pain is caused by injury to tissues outside the nervous system, such as the chronic pain of arthritis. NSAIDs function on the cellular level. They block the effects of enzymes particularly cyclo-oxygenase-1 (COX-1) and cyclo-oxygenase-2 (COX-2) enzymes which catalyze the conversion of arachidonic acid to inflammatory agents such as prostaglandins and prostacyclins. By simply blocking the cyclo-oxygenase enzymes, NSAIDs essentially prevent your body from producing prostaglandins. As a result, you feel less pain and decreased swelling. Mangosteen Benefits: Xanthones found in mangosteen function like a COX-2 inhibitor without eliciting the development of stomach ulcers. Gastrointestinal Problems: There are five types of prostaglandins in your body. One type of prostaglandin produced by COX-1 enzyme and an analog called Misoprostol helps protect the stomach lining. Regular intake of NSAIDs blocks COX-1 enzymes and thereby negating the protective function of the prostaglandin. Consequently, NSAIDs cause a significant increase in the prevalence of gastrointestinal problems such as diarrhea and indigestion. Hypertension and Renal Damage: The mechanism of renal damage spurred by NSAIDs is due to changes in renal hemodynamics. NSAIDs have been shown to reduce the blood flow to the kidneys and affect the function of the nephrons. As a result, salt and fluids are retained in your body. The higher the volume of salt and fluids in your bloodstream, the higher your blood pressure. If the problem goes unchecked, it can cause irreversible damage to your kidneys leading to eventual kidney failure, which may later require dialysis. Mangosteen Benefits: Recent studies have shown that Xanthones have
no harmful influence on blood coagulation and increases blood
perfusion rate in the kidneys, thereby enhancing renal function while
helping in the regulation of salt and fluid balance in the body.
Mangosteen
Benefits: Over the last three
decades, a lot of studies
on xanthones have proven its efficacy in treating various types of
allergies. This is due to the fact that xanthones block the formation
of histamines – substances that trigger the body’s allergic
response.
Allergic Reactions: Some people are allergic to NSAIDs and may develop dyspnea when an NSAID is taken. People with asthma are at a higher risk for having severe allergic reaction to NSAIDs. Health experts generally recommend that people with asthma refrain from taking NSAIDs. Aside from asthma, there are other allergic reactions that have been associated with NSAIDs, they range from mild to life threatening. The common reactions include skin affectations such as swelling and hives. There are also respiratory problems like rhinitis. What Is
A
COX-2 Inhibitor And What Are The Risks Of It?
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here for the testimonials Chronic inflammation can lead to Type II diabetes, cancer, arthritis, alzheimer's disease, heart disease and other deadly diseases. Xanthones in mangosteen naturally fight inflammation at the cellular level by inhibiting COX 2 enzymes. Invest In Your Health & Feel The Amazing Healing Power Of Mangosteen |